Stick New Migraine Medicine Up Your Nose
It’s not available yet and won’t be for years, but a promising new nasal spray is being developed by ROXRO Pharma (you think manybe a dog named the company?) This intranasal treatment, known as ROX-828, shoots a fine spray of NSAID ketorolac up your nose to be immediately absorbed into your system. It has produced promising results in a European clinical trial.
Why A Nasal Spray?
There are already ketorolac pills available, but they have whopping side effects. This is one of the most powerful NSAIDs legally available and is only advised for short term use. It’s usually given for post-operative pain, for example. It works on reducing hormones in your body that are though to contribute to pain making.
With a nasal spray, it’s hoped that not only will a migraine in progress be stopped, but that there will be less severe side effects. These stests are showing that a nasal spray can administer the medicine as quickly as a needle injection. So far, the studies are showing that the nasal spray works to alleviate migraine pain within two hours of spraying.
ROXRO is also working on a different formulation called ROX-888 which is has just completed its Pahase 3 Clinical trial in the US. The results are being compiled and it’s probably going to be a while to interpet them accurractely. ROXRO hopes to submit a “new drug” application to the FDA later this year.
And then the wait continues.
I could not find out how much this stuff is planning to cost. I expect it’ll be a whopper, even in comparison to preventative migraine medicines like Imitrex.
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