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More Buzz Over Gap Blockers For Migraines

by Rena Sherwood

Buzz is from England, so forgive the rah-rah imageThere’s a bit of a buzz throughout the British press about a class of migraine drugs called “gap blockers” that are available in the UK on a limited basis. Unfortunately, these drugs don’t remove Gap stores from the face of the planet. That’s another type of headache altogether. No, these gap blockers are to help prevent migraines by directly affecting brain chemistry to keep certain nuerons from firing. Many of these drugs are still in the clinical trial stage.

Don’t We Already Have Those?

There are a lot of drugs available to prevent migraines, including Imitrex (which yours truly might be moved onto soon if her current medication doesn’t pan out). However, these drugs tend to have some really heavy-duty side efffects, including asthma, hair loss and sudden wieght gain. There’s also the usual “risk of harming foetal development”, but that tends not to apply to most migraineurs because we’re too busy having migraines to have sex.

The big buzz about the gap junction blockers for migraines is that they work just as well as a drug like Imitrex, but without the side effects.

As a point of interest, an article in the Daily Telegraph went on to explain how migraines are treated:

Once attacks happen they can be treated with powerful painkillers such as codeine and anti sickness medication.

Day -YAM! When I lived in England, I was NEVER offered codeine for my multitide of migraines. Where’s my codeine? I think I’m due some codeine!

Tonabersat

Get used to that name if you have migraines. That’s suppossed to be THE migraine drug of the future, although it is still in development. It’ll probably cost an arm and both legs when it comes out. The good news (financially speaking) is that dosage seems to be less than for other drugs.

The thing that really, really bothers me about gap blockers is that I can’t remember if I ever wrote about them before on this blog along with other migraine drugs in development. Obviously, this is proof that all of my neurons definately aren’t firing.


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